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James Wisler
2006-07 Fellow
Cardiology Fellow, Duke University

What impact did the Sarnoff Fellowship year have on your career?

The Sarnoff Fellowship year allowed me the opportunity to explore my research interests. I subsequently decided to return to the institution where I completed my Sarnoff Fellowship year to complete residency training. In conjunction with my lab mentor from my Sarnoff year (Dr. Robert Lefkowitz), I elected to pursue training via the ABIM research track pathway and have resumed my research training in his laboratory as a Cardiology fellow. The entire arch of my career has thus been shaped and directed by my Sarnoff experience.

Why should medical students consider the Sarnoff Fellowship apart from other programs?

The Sarnoff Fellowship allows students the chance to explore research interests in any environment they wish and with a mentor of their choosing. For me, I was able to interview in numerous labs at multiple institutions. It was perhaps fortuitous that I felt most comfortably with the opportunity to pursue research training under a mentor who would later become the recipient of the 2012 Nobel Prize in Chemistry.

What are your professional aspirations?

I plan to finish my Cardiology fellowship in 2015 after which time I hope to be in position to have applied for and received young investigator funding such as a K award. In particular, I am interested in the physiologic and pharmacologic consequences of "non-canonical,” non-G-protein-mediated signaling via G-protein coupled receptors.

What is your greatest professional accomplishment?

This early in my career I would rate publishing a first author paper in the Proceedings of the National Academy of Sciences as my greatest professional accomplishment.
What is your most memorable Sarnoff moment? My most memorable Sarnoff moment would definitely be the time spent with other fellows at the American Heart Association Scientific Sessions as well as the Annual Meeting.

What are your hobbies?

I enjoying running, having completed over 15 marathons and ultra-marathons, as well as basketball and golf. In addition, my wife and I recently celebrated the birth of our third child (July 2012) and have very much enjoyed the transition from man-to-man to zone defense.
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